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Immunostimulated Arginase II Expression in Intestinal Epithelial Cells Reduces Nitric Oxide Production and Apoptosis

Increased production of nitric oxide (NO) and subsequent local cytotoxicity to mucosal epithelial cells has been proposed as a putative mechanism involved in the development of necrotizing enterocolitis (NEC). Intestinal epithelial cells (IECs) metabolize L-arginine to either nitric oxide (NO) by NO...

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Udgivet i:Front Cell Dev Biol
Main Authors: Talavera, Maria M., Nuthakki, Sushma, Cui, Hongmei, Jin, Yi, Liu, Yusen, Nelin, Leif D.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5331049/
https://ncbi.nlm.nih.gov/pubmed/28299311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2017.00015
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