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Mitochondrial biogenesis and proteome remodeling promotes one carbon metabolism for T cell activation
Naïve T cell stimulation activates anabolic metabolism to fuel the transition from quiescence to growth and proliferation. Here we show that naïve CD4(+) T cell activation induces a unique program of mitochondrial biogenesis and remodeling. Using mass spectrometry, we quantified protein dynamics dur...
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| Publicado no: | Cell Metab |
|---|---|
| Main Authors: | , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5330619/ https://ncbi.nlm.nih.gov/pubmed/27411012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2016.06.007 |
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