Inhibition of oncogenic transformation by mammalian Lin-9, a pRB-associated protein

Genetic studies in Caenorhabditis elegans identified lin-9 to function together with the retinoblastoma homologue lin-35 in vulva differentiation. We have now identified a human homologue of Lin-9 (hLin-9) and provide evidence about its function in the mammalian pRB pathway. hLin-9 binds to pRB and...

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Hlavní autoři: Gagrica, Sladjana, Hauser, Stefanie, Kolfschoten, Ingrid, Osterloh, Lisa, Agami, Reuven, Gaubatz, Stefan
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2004
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC533054/
https://ncbi.nlm.nih.gov/pubmed/15538385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600470
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