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The human synMuv-like protein LIN-9 is required for transcription of G2/M genes and for entry into mitosis

Regulated gene expression is critical for the proper timing of cell cycle transitions. Here we report that human LIN-9 has an important function in transcriptional regulation of G2/M genes. Depletion of LIN-9 by RNAi in human fibroblasts strongly impairs proliferation and delays progression from G2...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Osterloh, Lisa, von Eyss, Björn, Schmit, Fabienne, Rein, Lena, Hübner, Denise, Samans, Birgit, Hauser, Stefanie, Gaubatz, Stefan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782375/
https://ncbi.nlm.nih.gov/pubmed/17159899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601478
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