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The human synMuv-like protein LIN-9 is required for transcription of G2/M genes and for entry into mitosis
Regulated gene expression is critical for the proper timing of cell cycle transitions. Here we report that human LIN-9 has an important function in transcriptional regulation of G2/M genes. Depletion of LIN-9 by RNAi in human fibroblasts strongly impairs proliferation and delays progression from G2...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1782375/ https://ncbi.nlm.nih.gov/pubmed/17159899 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601478 |
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