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Overlapping and distinct pRb pathways in the mammalian auditory and vestibular organs
Retinoblastoma gene (Rb1) is required for proper cell cycle exit in the developing mouse inner ear and its deletion in the embryo leads to proliferation of sensory progenitor cells that differentiate into hair cells and supporting cells. In a conditional hair cell Rb1 knockout mouse, Pou4f3-Cre-pRb(...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3048802/ https://ncbi.nlm.nih.gov/pubmed/21239885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.2.14640 |
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