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Overlapping and distinct pRb pathways in the mammalian auditory and vestibular organs

Retinoblastoma gene (Rb1) is required for proper cell cycle exit in the developing mouse inner ear and its deletion in the embryo leads to proliferation of sensory progenitor cells that differentiate into hair cells and supporting cells. In a conditional hair cell Rb1 knockout mouse, Pou4f3-Cre-pRb(...

詳細記述

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書誌詳細
主要な著者: Huang, Mingqian, Sage, Cyrille, Tang, Yong, Lee, Sang Goo, Petrillo, Marco, Hinds, Philip W, Chen, Zheng-Yi
フォーマット: Artigo
言語:Inglês
出版事項: Landes Bioscience 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048802/
https://ncbi.nlm.nih.gov/pubmed/21239885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.2.14640
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