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Overlapping and distinct pRb pathways in the mammalian auditory and vestibular organs

Retinoblastoma gene (Rb1) is required for proper cell cycle exit in the developing mouse inner ear and its deletion in the embryo leads to proliferation of sensory progenitor cells that differentiate into hair cells and supporting cells. In a conditional hair cell Rb1 knockout mouse, Pou4f3-Cre-pRb(...

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Bibliografische gegevens
Hoofdauteurs: Huang, Mingqian, Sage, Cyrille, Tang, Yong, Lee, Sang Goo, Petrillo, Marco, Hinds, Philip W, Chen, Zheng-Yi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Landes Bioscience 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048802/
https://ncbi.nlm.nih.gov/pubmed/21239885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.2.14640
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