Overlapping and distinct pRb pathways in the mammalian auditory and vestibular organs

Retinoblastoma gene (Rb1) is required for proper cell cycle exit in the developing mouse inner ear and its deletion in the embryo leads to proliferation of sensory progenitor cells that differentiate into hair cells and supporting cells. In a conditional hair cell Rb1 knockout mouse, Pou4f3-Cre-pRb(...

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Bibliografiske detaljer
Main Authors: Huang, Mingqian, Sage, Cyrille, Tang, Yong, Lee, Sang Goo, Petrillo, Marco, Hinds, Philip W, Chen, Zheng-Yi
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2011
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Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048802/
https://ncbi.nlm.nih.gov/pubmed/21239885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.2.14640
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