Peptidoglycan recognition protein (PGRP)-LE and PGRP-LC act synergistically in Drosophila immunity

In innate immunity, pattern recognition molecules recognize cell wall components of microorganisms and activate subsequent immune responses, such as the induction of antimicrobial peptides and melanization in Drosophila. The diaminopimelic acid (DAP)-type peptidoglycan potently activates imd-depende...

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Bibliografiske detaljer
Main Authors: Takehana, Aya, Yano, Tamaki, Mita, Shizuka, Kotani, Atsushi, Oshima, Yoshiteru, Kurata, Shoichiro
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2004
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC533052/
https://ncbi.nlm.nih.gov/pubmed/15538387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600466
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