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Overexpression of a pattern-recognition receptor, peptidoglycan-recognition protein-LE, activates imd/relish-mediated antibacterial defense and the prophenoloxidase cascade in Drosophila larvae

In Drosophila, microbial infection activates an antimicrobial defense system involving the activation of proteolytic cascades in the hemolymph and intracellular signaling pathways, the immune deficiency (imd) and Toll pathways, in immune-responsive tissues. The mechanisms for microbial recognition a...

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Detalhes bibliográficos
Main Authors: Takehana, Aya, Katsuyama, Tomonori, Yano, Tamaki, Oshima, Yoshiteru, Takada, Haruhiko, Aigaki, Toshiro, Kurata, Shoichiro
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC129750/
https://ncbi.nlm.nih.gov/pubmed/12359879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.212301199
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