Overexpression of a pattern-recognition receptor, peptidoglycan-recognition protein-LE, activates imd/relish-mediated antibacterial defense and the prophenoloxidase cascade in Drosophila larvae

In Drosophila, microbial infection activates an antimicrobial defense system involving the activation of proteolytic cascades in the hemolymph and intracellular signaling pathways, the immune deficiency (imd) and Toll pathways, in immune-responsive tissues. The mechanisms for microbial recognition a...

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Bibliographic Details
Main Authors: Takehana, Aya, Katsuyama, Tomonori, Yano, Tamaki, Oshima, Yoshiteru, Takada, Haruhiko, Aigaki, Toshiro, Kurata, Shoichiro
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2002
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC129750/
https://ncbi.nlm.nih.gov/pubmed/12359879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.212301199
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