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Overexpression of a pattern-recognition receptor, peptidoglycan-recognition protein-LE, activates imd/relish-mediated antibacterial defense and the prophenoloxidase cascade in Drosophila larvae

In Drosophila, microbial infection activates an antimicrobial defense system involving the activation of proteolytic cascades in the hemolymph and intracellular signaling pathways, the immune deficiency (imd) and Toll pathways, in immune-responsive tissues. The mechanisms for microbial recognition a...

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Main Authors: Takehana, Aya, Katsuyama, Tomonori, Yano, Tamaki, Oshima, Yoshiteru, Takada, Haruhiko, Aigaki, Toshiro, Kurata, Shoichiro
格式: Artigo
語言:Inglês
出版: The National Academy of Sciences 2002
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC129750/
https://ncbi.nlm.nih.gov/pubmed/12359879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.212301199
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