Admixture mapping in two Mexican samples identifies significant associations of locus ancestry with triglyceride levels in the BUD13/ZNF259/APOA5 region and fine mapping points to rs964184 as the main driver of the association signal

We carried out an admixture mapping study of lipid traits in two samples from Mexico City. Native American locus ancestry was significantly associated with triglyceride levels in a broad region of chromosome 11 overlapping the BUD13, ZNF259 and APOA5 genes. In our fine-mapping analysis of this regio...

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Publicado en:PLoS One
Autores principales: Parra, Esteban J., Mazurek, Andrew, Gignoux, Christopher R., Sockell, Alexandra, Agostino, Michael, Morris, Andrew P., Petty, Lauren E., Hanis, Craig L., Cox, Nancy J., Valladares-Salgado, Adan, Below, Jennifer E., Cruz, Miguel
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2017
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5330487/
https://ncbi.nlm.nih.gov/pubmed/28245265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0172880
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