Admixture mapping in two Mexican samples identifies significant associations of locus ancestry with triglyceride levels in the BUD13/ZNF259/APOA5 region and fine mapping points to rs964184 as the main driver of the association signal

We carried out an admixture mapping study of lipid traits in two samples from Mexico City. Native American locus ancestry was significantly associated with triglyceride levels in a broad region of chromosome 11 overlapping the BUD13, ZNF259 and APOA5 genes. In our fine-mapping analysis of this regio...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Parra, Esteban J., Mazurek, Andrew, Gignoux, Christopher R., Sockell, Alexandra, Agostino, Michael, Morris, Andrew P., Petty, Lauren E., Hanis, Craig L., Cox, Nancy J., Valladares-Salgado, Adan, Below, Jennifer E., Cruz, Miguel
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2017
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5330487/
https://ncbi.nlm.nih.gov/pubmed/28245265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0172880
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