Admixture mapping in two Mexican samples identifies significant associations of locus ancestry with triglyceride levels in the BUD13/ZNF259/APOA5 region and fine mapping points to rs964184 as the main driver of the association signal

We carried out an admixture mapping study of lipid traits in two samples from Mexico City. Native American locus ancestry was significantly associated with triglyceride levels in a broad region of chromosome 11 overlapping the BUD13, ZNF259 and APOA5 genes. In our fine-mapping analysis of this regio...

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Bibliographic Details
Published in:PLoS One
Main Authors: Parra, Esteban J., Mazurek, Andrew, Gignoux, Christopher R., Sockell, Alexandra, Agostino, Michael, Morris, Andrew P., Petty, Lauren E., Hanis, Craig L., Cox, Nancy J., Valladares-Salgado, Adan, Below, Jennifer E., Cruz, Miguel
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5330487/
https://ncbi.nlm.nih.gov/pubmed/28245265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0172880
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