An HP1 isoform-specific feedback mechanism regulates Suv39h1 activity under stress conditions

The presence of H3K9me3 and heterochromatin protein 1 (HP1) are hallmarks of heterochromatin conserved in eukaryotes. The spreading and maintenance of H3K9me3 is effected by the functional interplay between the H3K9me3-specific histone methyltransferase Suv39h1 and HP1. This interplay is complex in...

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Vydáno v:Epigenetics
Hlavní autoři: Raurell-Vila, Helena, Bosch-Presegue, Laia, Gonzalez, Jessica, Kane-Goldsmith, Noriko, Casal, Carmen, Brown, Jeremy P., Marazuela-Duque, Anna, Singh, Prim B., Serrano, Lourdes, Vaquero, Alejandro
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2017
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5330444/
https://ncbi.nlm.nih.gov/pubmed/28059589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2016.1278096
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