Llwytho...

Influences of BRAF Inhibitors on the Immune Microenvironment and the Rationale for Combined Molecular and Immune Targeted Therapy

The identification of key driver mutations in melanoma has led to the development of targeted therapies aimed at BRAF and MEK, but responses are often limited in duration. There is growing evidence that MAPK pathway activation impairs antitumor immunity and that targeting this pathway may enhance re...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Curr Oncol Rep
Prif Awduron: Reddy, Sangeetha M., Reuben, Alexandre, Wargo, Jennifer A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5330383/
https://ncbi.nlm.nih.gov/pubmed/27215436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11912-016-0531-z
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