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Studies at the Ionizable Position of Cephalosporins and Penicillins: Hydroxamates as Substitutes for the Traditional Carboxylate Group

Classically, β-lactams need an ionizable group to potentiate antibacterial activity. Sets of cephalosporins and penicillins featuring different substituted hydroxamates in place of the traditional carboxylate group have been synthesized and tested for antibiotic activity. Many of the compounds exhib...

詳細記述

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書誌詳細
出版年:J Antibiot (Tokyo)
主要な著者: Majewski, Mark W., Miller, Patricia A., Miller, Marvin J.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5329033/
https://ncbi.nlm.nih.gov/pubmed/27999444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ja.2016.149
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