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An Exploration of Charge Compensating Ion Channels across the Phagocytic Vacuole of Neutrophils

Neutrophils phagocytosing bacteria and fungi exhibit a burst of non-mitochondrial respiration that is required to kill and digest the engulfed microbes. This respiration is accomplished by the movement of electrons across the wall of the phagocytic vacuole by the neutrophil NADPH oxidase, NOX2. In t...

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Udgivet i:Front Pharmacol
Main Authors: Foote, Juliet R., Behe, Philippe, Frampton, Mathew, Levine, Adam P., Segal, Anthony W.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5329019/
https://ncbi.nlm.nih.gov/pubmed/28293191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00094
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