Factors governing helical preference of peptides containing multiple alpha,alpha-dialkyl amino acids.

The presence of multiple alpha,alpha-dialkyl amino acids such as alpha-methylalanine (alpha-aminoisobutyric acid, Aib) leads to predominantly helical structures, either with alpha-helical or 3(10)-helical hydrogen bonding patterns. The crystal structure of emerimicin-(1-9) benzyl ester (Ac-Phe-Aib-A...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Marshall, G R, Hodgkin, E E, Langs, D A, Smith, G D, Zabrocki, J, Leplawy, M T
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53289/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2296604/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.1.487
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