Factors governing helical preference of peptides containing multiple alpha,alpha-dialkyl amino acids.
The presence of multiple alpha,alpha-dialkyl amino acids such as alpha-methylalanine (alpha-aminoisobutyric acid, Aib) leads to predominantly helical structures, either with alpha-helical or 3(10)-helical hydrogen bonding patterns. The crystal structure of emerimicin-(1-9) benzyl ester (Ac-Phe-Aib-A...
Guardat en:
| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1990
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53289/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2296604/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.1.487 |
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