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Regulation of High Glucose-Induced Apoptosis of Brain Pericytes by Mitochondrial CA VA: A Specific Target for Prevention of Diabetic Cerebrovascular Pathology
Events responsible for cerebrovascular disease in diabetes are not fully understood. Pericyte loss is an early event that leads to endothelial cell death, microaneurysms, and cognitive impairment. A biochemical mechanism underlying pericyte loss is rapid respiration (oxidative metabolism of glucose)...
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| Publicado no: | Biochim Biophys Acta |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5328884/ https://ncbi.nlm.nih.gov/pubmed/28131914 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2017.01.025 |
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