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Pharmacological Inhibition of Mitochondrial Carbonic Anhydrases Protects Mouse Cerebral Pericytes from High Glucose-Induced Oxidative Stress and Apoptosis

Diabetes-associated complications in the microvasculature of the brain are caused by oxidative stress, generated by overproduction of reactive oxygen species from hyperglycemia-induced accelerated oxidative metabolism of glucose. Pericytes, essential for the viability of the microvasculature, are es...

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Detalhes bibliográficos
Main Authors: Shah, Gul N., Price, Tulin O., Banks, William A., Morofuji, Yoichi, Kovac, Andrej, Ercal, Nuran, Sorenson, Christine M., Shin, Eui S., Sheibani, Nader
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583505/
https://ncbi.nlm.nih.gov/pubmed/23249625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.112.201400
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