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High Glucose-Induced Mitochondrial Respiration and Reactive Oxygen Species in Mouse Cerebral Pericytes is Reversed by Pharmacological Inhibition of Mitochondrial Carbonic Anhydrases: Implications for Cerebral Microvascular Disease in Diabetes

Hyperglycemia-induced oxidative stress leads to diabetes-associated damage to the microvasculature of the brain. Pericytes in close proximity to endothelial cells in the brain microvessels are vital to the integrity of the blood-brain barrier and are especially susceptible to oxidative stress. Accor...

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Detalhes bibliográficos
Main Authors: Shah, Gul N., Morofuji, Yoichi, Banks, William A., Price, Tulin O.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3875343/
https://ncbi.nlm.nih.gov/pubmed/24076121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2013.09.086
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