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Collagen IV Diseases: A Focus on the Glomerular Basement Membrane in Alport Syndrome
Alport syndrome is the result of mutations in any of three type IV collagen genes, COL4A3, COL4A4, or COL4A5. Because the three collagen chains form heterotrimers, there is an absence of all three proteins in the basement membranes where they are expressed. In the glomerulus, the mature glomerular b...
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| Publicado en: | Matrix Biol |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5328792/ https://ncbi.nlm.nih.gov/pubmed/27576055 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2016.08.005 |
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