Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions

Canonical Wnt/β-catenin signaling has central roles in development and diseases, and is initiated by the action of the frizzled (Fz) receptor, its coreceptor LDL receptor-related protein 6 (Lrp6), and the cytoplasmic dishevelled (Dvl) protein. The functional relationships among Fz, Lrp6 and Dvl have...

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Dettagli Bibliografici
Pubblicato in:Development
Autori principali: Zeng, Xin, Huang, He, Tamai, Keiko, Zhang, Xinjun, Harada, Yuko, Yokota, Chika, Almeida, Karla, Wang, Jianbo, Doble, Brad, Woodgett, Jim, Wynshaw-Boris, Anthony, Hsieh, Jen-Chieh, He, Xi
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328672/
https://ncbi.nlm.nih.gov/pubmed/18077588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.013540
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