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Reaction Pathway for Cocaine Hydrolase-Catalyzed Hydrolysis of (+)-Cocaine

A recently designed and discovered cocaine hydrolase (CocH), engineered from human butyrylcholinesterase (BChE), has been proven promising as a novel enzyme therapy for treatment of cocaine overdose and addiction because it is highly efficient in catalyzing hydrolysis of naturally occurring (−)-coca...

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Bibliografski detalji
Izdano u:Theor Chem Acc
Glavni autori: Yao, Yuan, Liu, Junjun, Zheng, Fang, Zhan, Chang-Guo
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328586/
https://ncbi.nlm.nih.gov/pubmed/28250715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00214-015-1788-2
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