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Reaction Pathway for Cocaine Hydrolase-Catalyzed Hydrolysis of (+)-Cocaine
A recently designed and discovered cocaine hydrolase (CocH), engineered from human butyrylcholinesterase (BChE), has been proven promising as a novel enzyme therapy for treatment of cocaine overdose and addiction because it is highly efficient in catalyzing hydrolysis of naturally occurring (−)-coca...
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| Publicat a: | Theor Chem Acc |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5328586/ https://ncbi.nlm.nih.gov/pubmed/28250715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00214-015-1788-2 |
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