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In Vivo Fitness Adaptations of Colistin-Resistant Acinetobacter baumannii Isolates to Oxidative Stress

The loss of fitness in colistin-resistant (CR) Acinetobacter baumannii was investigated using longitudinal isolates from the same patient. Early CR isolates were outcompeted by late CR isolates for growth in broth and survival in the lungs of mice. Fitness loss was associated with an increased susce...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Jones, Crystal L., Singh, Shweta S., Alamneh, Yonas, Casella, Leila G., Ernst, Robert K., Lesho, Emil P., Waterman, Paige E., Zurawski, Daniel V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328574/
https://ncbi.nlm.nih.gov/pubmed/27993849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00598-16
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