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In Vivo Fitness Adaptations of Colistin-Resistant Acinetobacter baumannii Isolates to Oxidative Stress

The loss of fitness in colistin-resistant (CR) Acinetobacter baumannii was investigated using longitudinal isolates from the same patient. Early CR isolates were outcompeted by late CR isolates for growth in broth and survival in the lungs of mice. Fitness loss was associated with an increased susce...

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Publicat a:Antimicrob Agents Chemother
Autors principals: Jones, Crystal L., Singh, Shweta S., Alamneh, Yonas, Casella, Leila G., Ernst, Robert K., Lesho, Emil P., Waterman, Paige E., Zurawski, Daniel V.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328574/
https://ncbi.nlm.nih.gov/pubmed/27993849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00598-16
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