Impaired Virulence and Fitness of a Colistin-Resistant Clinical Isolate of Acinetobacter baumannii in a Rat Model of Pneumonia

We compared the fitness and lung pathogenicity of two isogenic clinical isolates of Acinetobacter baumannii, one resistant (ABCR) and the other susceptible (ABCS) to colistin. In vitro, ABCR exhibited slower growth kinetics than ABCS. In a rat model of pneumonia, ABCR was associated with less pronou...

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Detaylı Bibliyografya
Asıl Yazarlar: Hraiech, Sami, Roch, Antoine, Lepidi, Hubert, Atieh, Thérèse, Audoly, Gilles, Rolain, Jean-Marc, Raoult, Didier, Brunel, Jean-Michel, Papazian, Laurent, Brégeon, Fabienne
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2013
Konular:
Mechanisms of Resistance
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811450/
https://ncbi.nlm.nih.gov/pubmed/23836181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00700-13
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