Pharmacological Blockade of the Chemokine Receptor CCR1 Protects Mice from Systemic Candidiasis of Hematogenous Origin

Systemic candidiasis is a leading cause of nosocomial bloodstream infection with a high mortality rate despite treatment. Immune-based strategies are needed to improve outcomes. We previously reported that genetic deficiency in the chemokine receptor CCR1 improves survival and ameliorates tissue dam...

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Detaylı Bibliyografya
Yayımlandı:Antimicrob Agents Chemother
Asıl Yazarlar: Lionakis, Michail S., Albert, Nathaniel D., Swamydas, Muthulekha, Lee, Chyi-Chia R., Loetscher, Pius, Kontoyiannis, Dimitrios P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2017
Konular:
Experimental Therapeutics
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328547/
https://ncbi.nlm.nih.gov/pubmed/27993850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02365-16
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