Chemokine Receptor Ccr1 Drives Neutrophil-Mediated Kidney Immunopathology and Mortality in Invasive Candidiasis

Invasive candidiasis is the 4(th) leading cause of nosocomial bloodstream infection in the US with mortality that exceeds 40% despite administration of antifungal therapy; neutropenia is a major risk factor for poor outcome after invasive candidiasis. In a fatal mouse model of invasive candidiasis t...

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Main Authors: Lionakis, Michail S., Fischer, Brett G., Lim, Jean K., Swamydas, Muthulekha, Wan, Wuzhou, Richard Lee, Chyi-Chia, Cohen, Jeffrey I., Scheinberg, Phillip, Gao, Ji-Liang, Murphy, Philip M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2012
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3420964/
https://ncbi.nlm.nih.gov/pubmed/22916017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002865
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