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Genetic deletion of chemokine receptor Ccr7 exacerbates atherogenesis in ApoE-deficient mice

AIMS: Recent evidence suggests that both Ccr7 and its ligands, Ccl19 and Ccl21, are present in mouse and human atherosclerotic plaques; however, the role of Ccr7 in atherogenesis is still controversial. Here, we addressed this question by using the classic apolipoprotein E-deficient (ApoE(−/−)) mous...

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Autors principals: Wan, Wuzhou, Lionakis, Michail S., Liu, Qian, Roffê, Ester, Murphy, Philip M.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567784/
https://ncbi.nlm.nih.gov/pubmed/23180724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvs349
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