High-Dose Ampicillin-Sulbactam Combinations Combat Polymyxin-Resistant Acinetobacter baumannii in a Hollow-Fiber Infection Model

Acinetobacter baumannii is emerging with resistance to polymyxins. In 24-h time-kill experiments, high-dose ampicillin-sulbactam in combination with meropenem and polymyxin B achieved additivity or synergy against 10(8) CFU/ml of two clinical A. baumannii isolates resistant to all three drugs (maxim...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Lenhard, Justin R., Smith, Nicholas M., Bulman, Zackery P., Tao, Xun, Thamlikitkul, Visanu, Shin, Beom S., Nation, Roger L., Li, Jian, Bulitta, Jürgen B., Tsuji, Brian T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2017
Schlagworte:
Pharmacology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328540/
https://ncbi.nlm.nih.gov/pubmed/28052852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01268-16
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge