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Nonnucleoside Reverse Transcriptase Inhibitors Reduce HIV-1 Production from Latently Infected Resting CD4(+) T Cells following Latency Reversal

Therapeutic strategies that target the latent HIV-1 reservoir in resting CD4(+) T cells of infected individuals are always administered in the presence of combination antiretroviral therapy. Using a primary cell of HIV-1 latency, we evaluated whether different antiviral drug classes affected latency...

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Publicat a:Antimicrob Agents Chemother
Autors principals: Zerbato, Jennifer M., Tachedjian, Gilda, Sluis-Cremer, Nicolas
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328526/
https://ncbi.nlm.nih.gov/pubmed/27993846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01736-16
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