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Potent Nonnucleoside Reverse Transcriptase Inhibitors Target HIV-1 Gag-Pol

Nonnucleoside reverse transcriptase inhibitors (NNRTIs) target HIV-1 reverse transcriptase (RT) by binding to a pocket in RT that is close to, but distinct, from the DNA polymerase active site and prevent the synthesis of viral cDNA. NNRTIs, in particular, those that are potent inhibitors of RT poly...

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Detalhes bibliográficos
Main Authors: Figueiredo, Anna, Moore, Katie L, Mak, Johnson, Sluis-Cremer, Nicolas, de Bethune, Marie-Pierre, Tachedjian, Gilda
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635531/
https://ncbi.nlm.nih.gov/pubmed/17096588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.0020119
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