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Potent Nonnucleoside Reverse Transcriptase Inhibitors Target HIV-1 Gag-Pol

Nonnucleoside reverse transcriptase inhibitors (NNRTIs) target HIV-1 reverse transcriptase (RT) by binding to a pocket in RT that is close to, but distinct, from the DNA polymerase active site and prevent the synthesis of viral cDNA. NNRTIs, in particular, those that are potent inhibitors of RT poly...

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Bibliografische gegevens
Hoofdauteurs: Figueiredo, Anna, Moore, Katie L, Mak, Johnson, Sluis-Cremer, Nicolas, de Bethune, Marie-Pierre, Tachedjian, Gilda
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2006
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635531/
https://ncbi.nlm.nih.gov/pubmed/17096588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.0020119
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