Differential Macrophage Polarization from Pneumocystis in Immunocompetent and Immunosuppressed Hosts: Potential Adjunctive Therapy during Pneumonia

We explored differential polarization of macrophages during infection using a rat model of Pneumocystis pneumonia. We observed enhanced pulmonary M1 macrophage polarization in immunosuppressed (IS) hosts, but an M2 predominant response in immunocompetent (IC) hosts following Pneumocystis carinii cha...

Full description

Saved in:
Bibliographic Details
Published in:Infect Immun
Main Authors: Nandakumar, Vijayalakshmi, Hebrink, Deanne, Jenson, Paige, Kottom, Theodore, Limper, Andrew H.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2017
Subjects:
Fungal and Parasitic Infections
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328482/
https://ncbi.nlm.nih.gov/pubmed/27993972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00939-16
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items