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Evidence for Proinflammatory β-1,6 Glucans in the Pneumocystis carinii Cell Wall

Inflammation is a major cause of respiratory impairment during Pneumocystis pneumonia. Studies support a significant role for cell wall β-glucans in stimulating inflammatory responses. Fungal β-glucans are comprised of d-glucose homopolymers containing β-1,3-linked glucose backbones with β-1,6-linke...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Kottom, Theodore J., Hebrink, Deanne M., Jenson, Paige E., Gudmundsson, Gunnar, Limper, Andrew H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468544/
https://ncbi.nlm.nih.gov/pubmed/25916991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00196-15
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