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Mathematical modeling links Wnt signaling to emergent patterns of metabolism in colon cancer

Cell‐intrinsic metabolic reprogramming is a hallmark of cancer that provides anabolic support to cell proliferation. How reprogramming influences tumor heterogeneity or drug sensitivities is not well understood. Here, we report a self‐organizing spatial pattern of glycolysis in xenograft colon tumor...

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Detalhes bibliográficos
Publicado no:Mol Syst Biol
Main Authors: Lee, Mary, Chen, George T, Puttock, Eric, Wang, Kehui, Edwards, Robert A, Waterman, Marian L, Lowengrub, John
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5327728/
https://ncbi.nlm.nih.gov/pubmed/28183841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20167386
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