Wnt signaling directs a metabolic program of glycolysis and angiogenesis in colon cancer

Much of the mechanism by which Wnt signaling drives proliferation during oncogenesis is attributed to its regulation of the cell cycle. Here, we show how Wnt/β-catenin signaling directs another hallmark of tumorigenesis, namely Warburg metabolism. Using biochemical assays and fluorescence lifetime i...

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Detalhes bibliográficos
Main Authors: Pate, Kira T, Stringari, Chiara, Sprowl-Tanio, Stephanie, Wang, Kehui, TeSlaa, Tara, Hoverter, Nate P, McQuade, Miriam M, Garner, Chad, Digman, Michelle A, Teitell, Michael A, Edwards, Robert A, Gratton, Enrico, Waterman, Marian L
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4194089/
https://ncbi.nlm.nih.gov/pubmed/24825347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201488598
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