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Wnt signaling and colon carcinogenesis: Beyond APC

Activation of the Wnt signaling pathway via mutation of the adenomatous polyposis coli gene (APC) is a critical event in the development of colon cancer. For colon carcinogenesis, however, constitutive signaling through the canonical Wnt pathway is not a singular event. Here we review how canonical...

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Bibliographic Details
Main Authors: Najdi, Rani, Holcombe, Randall F., Waterman, Marian L.
Format: Artigo
Language:Inglês
Published: Medknow Publications 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3072659/
https://ncbi.nlm.nih.gov/pubmed/21483657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1477-3163.78111
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