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Wnt signaling and colon carcinogenesis: Beyond APC
Activation of the Wnt signaling pathway via mutation of the adenomatous polyposis coli gene (APC) is a critical event in the development of colon cancer. For colon carcinogenesis, however, constitutive signaling through the canonical Wnt pathway is not a singular event. Here we review how canonical...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Medknow Publications
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3072659/ https://ncbi.nlm.nih.gov/pubmed/21483657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1477-3163.78111 |
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