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Expression of Wnt ligands and Frizzled receptors in colonic mucosa and in colon carcinoma

Aims: Signalling through the Wnt pathway is integrally associated with colon carcinogenesis. Although activating mutations in the genes for adenomatous polyposis coli (APC) and β-catenin are clearly associated with colon cancer, less is understood about the role of the upstream secreted ligands (Wnt...

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Autors principals: Holcombe, R F, Marsh, J L, Waterman, M L, Lin, F, Milovanovic, T, Truong, T
Format: Artigo
Idioma:Inglês
Publicat: British Medical Journal Publishing Group 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1187182/
https://ncbi.nlm.nih.gov/pubmed/12147710
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