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PARP inhibitors: review of mechanisms of action and BRCA1/2 mutation targeting
Poly(ADP-ribose) polymerases have shown true promise in early clinical studies due to reported activity in BRCA-associated cancers. PARP inhibitors may represent a potentially important new class of chemotherapeutic agents directed at targeting cancers with defective DNA-damage repair. In order to w...
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| Udgivet i: | Prz Menopauzalny |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Termedia Publishing House
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5327624/ https://ncbi.nlm.nih.gov/pubmed/28250726 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5114/pm.2016.65667 |
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