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PARP Inhibitors for BRCA1/2 mutation-associated and BRCA-like malignancies
Poly(ADP-ribose)polymerase inhibitors (PARPis) have shown promising activity in patients with BRCA1/2 mutation-associated (BRCA1/2(MUT+)) ovarian and breast cancers. Accumulating evidence suggests that PARPi may have a wider application in the treatment of sporadic high-grade serous ovarian cancer,...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3868320/ https://ncbi.nlm.nih.gov/pubmed/24225019 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/annonc/mdt384 |
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