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PARP Inhibitors for BRCA1/2 mutation-associated and BRCA-like malignancies

Poly(ADP-ribose)polymerase inhibitors (PARPis) have shown promising activity in patients with BRCA1/2 mutation-associated (BRCA1/2(MUT+)) ovarian and breast cancers. Accumulating evidence suggests that PARPi may have a wider application in the treatment of sporadic high-grade serous ovarian cancer,...

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Detalhes bibliográficos
Main Authors: Lee, J-m., Ledermann, J. A., Kohn, E. C.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868320/
https://ncbi.nlm.nih.gov/pubmed/24225019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/annonc/mdt384
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