Influence of extracellular zinc on M1 microglial activation

Extracellular zinc, which is released from hippocampal neurons in response to brain ischaemia, triggers morphological changes in microglia. Under ischaemic conditions, microglia exhibit two opposite activation states (M1 and M2 activation), which may be further regulated by the microenvironment. We...

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Udgivet i:Sci Rep
Main Authors: Higashi, Youichirou, Aratake, Takaaki, Shimizu, Shogo, Shimizu, Takahiro, Nakamura, Kumiko, Tsuda, Masayuki, Yawata, Toshio, Ueba, Tetuya, Saito, Motoaki
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5327400/
https://ncbi.nlm.nih.gov/pubmed/28240322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43778
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