Influence of extracellular zinc on M1 microglial activation

Extracellular zinc, which is released from hippocampal neurons in response to brain ischaemia, triggers morphological changes in microglia. Under ischaemic conditions, microglia exhibit two opposite activation states (M1 and M2 activation), which may be further regulated by the microenvironment. We...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Higashi, Youichirou, Aratake, Takaaki, Shimizu, Shogo, Shimizu, Takahiro, Nakamura, Kumiko, Tsuda, Masayuki, Yawata, Toshio, Ueba, Tetuya, Saito, Motoaki
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5327400/
https://ncbi.nlm.nih.gov/pubmed/28240322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43778
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