Stimulation of brain nicotinic acetylcholine receptors activates adrenomedullary outflow via brain inducible NO synthase‐mediated S‐nitrosylation

BACKGROUND AND PURPOSE: We have demonstrated that i.c.v.‐administered (±)‐epibatidine, a nicotinic ACh receptor (nAChR) agonist, induced secretion of noradrenaline and adrenaline (catecholamines) from the rat adrenal medulla with dihydro‐β‐erythroidin (an α4β2 nAChR antagonist)‐sensitive brain mecha...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Higashi, Youichirou, Shimizu, Takahiro, Yamamoto, Masaki, Tanaka, Kenjiro, Yawata, Toshio, Shimizu, Shogo, Zou, Suo, Ueba, Tetsuya, Yuri, Kazunari, Saito, Motoaki
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6135790/
https://ncbi.nlm.nih.gov/pubmed/30007012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14445
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