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Aberrant Signaling through the HER2-ERK1/2 Pathway is Predictive of Reduced Disease-Free and Overall Survival in Early Stage Non-Small Cell Lung Cancer (NSCLC) Patients

Background: Purpose of this study was to evaluate the contribution of the Extracellular-regulated protein kinase (ERK)-1/2 pathway to oncogenic signaling elicited by the tyrosine kinase receptor HER2 in Non-Small Cell Lung Cancer (NSCLC) and to assess the prognostic value of these oncoproteins in NS...

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Detalhes bibliográficos
Publicado no:J Cancer
Main Authors: Scrima, Marianna, Zito Marino, Federica, Oliveira, Duarte Mendes, Marinaro, Cinzia, La Mantia, Elvira, Rocco, Gaetano, De Marco, Carmela, Malanga, Donatella, De Rosa, Nicla, Rizzuto, Antonia, Botti, Gerardo, Franco, Renato, Zoppoli, Pietro, Viglietto, Giuseppe
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5327372/
https://ncbi.nlm.nih.gov/pubmed/28243327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.17093
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