Aberrant Signaling through the HER2-ERK1/2 Pathway is Predictive of Reduced Disease-Free and Overall Survival in Early Stage Non-Small Cell Lung Cancer (NSCLC) Patients

Background: Purpose of this study was to evaluate the contribution of the Extracellular-regulated protein kinase (ERK)-1/2 pathway to oncogenic signaling elicited by the tyrosine kinase receptor HER2 in Non-Small Cell Lung Cancer (NSCLC) and to assess the prognostic value of these oncoproteins in NS...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Cancer
Auteurs principaux: Scrima, Marianna, Zito Marino, Federica, Oliveira, Duarte Mendes, Marinaro, Cinzia, La Mantia, Elvira, Rocco, Gaetano, De Marco, Carmela, Malanga, Donatella, De Rosa, Nicla, Rizzuto, Antonia, Botti, Gerardo, Franco, Renato, Zoppoli, Pietro, Viglietto, Giuseppe
Format: Artigo
Langue:Inglês
Publié: Ivyspring International Publisher 2017
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5327372/
https://ncbi.nlm.nih.gov/pubmed/28243327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.17093
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