11R-P53 and GM-CSF Expressing Oncolytic Adenovirus Target Cancer Stem Cells with Enhanced Synergistic Activity

Targeting cancer stem cells with oncolytic virus (OV) holds great potential for thorough elimination of cancer cells. Based on our previous studies, we here established 11R-P53 and mGM-CSF carrying oncolytic adenovirus (OAV) SG655-mGMP and investigated its therapeutic effect on hepatocellular carcin...

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Veröffentlicht in:J Cancer
Hauptverfasser: Lv, Sai-qun, Ye, Zhen-long, Liu, Pin-yi, Huang, Yao, Li, Lin-fang, Liu, Hui, Zhu, Hai-li, Jin, Hua-jun, Qian, Qi-jun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ivyspring International Publisher 2017
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5327369/
https://ncbi.nlm.nih.gov/pubmed/28243324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.16406
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